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Kgothatso Keeps Up With Medicine: Research ethics committee

25 June 2024

Fifth-year student doctor Kgothatso Legong discusses the utility of ethics committees in medical research.

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Ethics committees play a crucial role in ensuring that research conducted in various fields adhere to ethical principles and guidelines. These committees are responsible for reviewing research proposals, monitoring ongoing studies, and ensuring the protection of human subjects involved in research. The role of ethics committees in research is essential to uphold the integrity and moral standards of scientific investigations.

One of the primary reasons why ethics committees are necessary in research is to protect the rights and welfare of participants. Research involving human subjects has the potential to impact individuals physically, mentally, and emotionally. It is imperative that researchers conduct their studies in a manner that respects the autonomy, privacy, and dignity of participants. Ethics committees are tasked with reviewing research protocols to ensure that participants are fully informed about the risks and benefits of participation, provide voluntary consent, and are protected from harm.

Additionally, ethics committees help researchers navigate the complex ethical landscape of research. In an increasingly globalized world, cultural differences, beliefs, and norms must be considered when conducting research with diverse populations. Ethics committees provide guidance on how to navigate these differences and ensure that research is conducted in a culturally sensitive and respectful manner. By considering these factors, researchers can build trust and establish positive relationships with participants, which is essential for the success of research studies.

Historically, there have been several cases where experimental research was unethical due to the lack of oversight by ethics committees. One of the most infamous examples is the Tuskegee Syphilis Study conducted by the United States Public Health Service from 1932 to 1972. In this study, African American men with syphilis were left untreated and were not informed about their diagnosis or the purpose of the study. The men were deceived and were denied treatment that could have cured them of the disease. This unethical study led to the deaths of several participants and sparked outrage in the scientific community, ultimately leading to the establishment of stricter ethical guidelines for research involving human subjects.

Another example of unethical research is the Stanford Prison Experiment conducted by psychologist Philip Zimbardo in 1971. In this study, college students were randomly assigned to the roles of prisoners and guards in a simulated prison environment. The study was supposed to last two weeks but had to be terminated after only six days due to the extreme psychological distress experienced by participants. The guards exhibited abusive behaviour towards the prisoners, and the study lacked proper safeguards to protect the well-being of participants. This study raised serious ethical concerns about the treatment of human subjects in research and highlighted the importance of ethics committees in ensuring the ethical conduct of studies.

In response to such unethical research practices, ethics committees were established to review research proposals, monitor ongoing studies, and ensure that research is conducted in accordance with ethical principles. These committees are typically composed of experts in various fields, including researchers, ethicists, legal experts, and community representatives. Their primary role is to evaluate research protocols to ensure that they comply with ethical standards and guidelines set forth by regulatory bodies.

In summary, ethics committees play a crucial role in research by upholding ethical standards, protecting the rights and welfare of participants, and ensuring the integrity of scientific investigations. By providing guidance and oversight, ethics committees help researchers conduct studies in a manner that is respectful, transparent, and socially responsible. Through their work, ethics committees contribute to the advancement of knowledge and foster trust in the scientific community. It is essential that researchers and institutions adhere to ethical principles and guidelines to ensure the ethical conduct of research and prevent the repetition of past unethical practices.

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